Thursday, October 25, 2012

Frailty in Men and Low Levels of Testosterone

Most people believe that frailty in elderly people is a natural part of the aging process. This isnt necessarily so. Sometimes theres an underlying hormone, vitamin, or nutrient deficiency that leads to frailty in the elderly. Now, a new study shows that frailty in elderly men is associated with a low level of testosterone.

Low Levels of Testosterone and Frailty in the Elderly

Researchers used a special scale to assess the degree of frailty in a group of men over the age of seventy. They also measured their testosterone levels. After establishing their baseline levels of testosterone and degree of frailty, they retested them again more than four years later. The results? Men with low levels of testosterone were more likely to become frail as they grew older.

What are the Dangers of Frailty in Elderly Men?

Frailty in elderly men increases the risk of a variety of problems. Frailty in the elderly may can manifest as muscle weakness, loss of muscle mass, weight loss, decreased endurance, reduced walking speed, and an increased risk of falls and fractures. Elderly men who are frail are more likely to need assistance carrying out their daily activities and have a higher risk of institutionalization. The problem may be worsened if an elderly person also has other medical problems. Low levels of testosterone also increase the risk of osteoporosis - another risk factor for falls and fractures.

Can Testosterone Supplementation Reduce Frailty in Elderly Men?

More studies are needed to see whether testosterone supplements can prevent or improve frailty in older men. One study showed that elderly men with borderline low levels of testosterone who were supplemented with testosterone for six months experienced an increase in muscle strength and mass - although this didnt translate into functional improvements. On the other hand, researchers pointed out that testosterone levels may need to be even higher to improve functional limitations.

Frailty in Elderly Men and Testosterone

The verdict is still out as to whether boosting testosterone levels in men who are deficient prevents frailty. What is known is that low levels of testosterone increases the risk of becoming frail with age and that replacing testosterone improves muscle strength and mass - but not necessarily functional abilities. It may be a good idea for men over the age of seventy to have a testosterone level checked and talk to a doctor about whether replacement therapy is a good option for them.

References:

http://www.medscape.com/viewarticle/723985?sssdmh=dm1.623422&src=nldne&uac=65946DY

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